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The purpose of this research was produced the learning material based guided inquiry that appropriate to be used to improve students’ science literacy skills on solubility and solubility product. The development of learning material used the R&D method and was implemented to 20 students of class XI IPA 1 Muhammadiyah 4 Senior High School Surabaya in academic year 2016/2017 with one group pretest-posttest design. The data collection techniques were validation, observation, test, and questionnaire. The results of this research showed that: 1) the developed learning material such as lesson plan, worksheet, and science literacy skill tests are valid with good and excellent category; 2) each of the learning phases in lesson plan has been well to excellent implemented; 3) the dominant student activity is to discuss with one group’s friend; 4) learning material and learning process get positive response from students; and 5) the science literacy skills of all student increases by getting the n-gain score with medium and high category. It’s conclusion that the developed learning material based guided inquiry were appropriate to be used and effective to improve students’ science literacy skills on solubility and solubility product.

learning material, guided inquiry, science literacy skill