The use of nanogold as a leprosy drug because it has activity increases cell proliferation and increases collagen biosynthesis. These two activities are very necessary in the process of recovery and closure of wounds, including in leprosy. The nanosilver as an anti-bacterial material includes the leprosy bacteria Mycobacterium Leprae. The combination of the two in leprosy medicine is theoretically very suitable and promises optimal results. The big question is whether the combined application of nanogold and nanosilver has been proven to cure leprosy. This study applied a combination of nanogold and nanosilver in 30 leprosy patients who still consumed leprosy drugs. The results were compared with 30 other patients who only consumed leprosy drugs. Retrieval of data by medical experts is done every 2 weeks for 3 months. Data in the form of medical indicators are wound recovery (width and pain), body temperature, blood pressure, heart rate and skin surface softness. The results obtained by patients with treatment using nanogold and nanosilver healed significantly faster than patients without treatment. Conclusions of the combination of nanogold and nanosilver accelerate the healing process of leprosy patients. This research has a very good impact on the medical world so it is very necessary to apply it to various other types of diseases. Nanogold and nanosilver can be relied upon for future medicine for some diseases.