Scientific literacy is one of main skills students should have in the 21st century. One method to train scientific literacy is by writing scientific article. The purpose of the study was to improve scientific writing of students in exploration of local wisdom in East Java on Conservation of Natural Resources and Environment (CNRE) course. Indicators of scientific literation expected including formulation of problems, data collection in local region, data analysis, and formulation of conclusions based on study conducted. Respondents were consisted of five classes of year 2019 students in Department of Biology programming CNRE course; 2 classes of Biology study program and 3 classes of Biology Education study program, divided into 37 groups. Each group wrote scientific article based on local wisdom found in their local region. Data was analyzed using quantitative descriptive analysis. Results showed that scientific literacy training through scientific writing in CNRE course was successful, as indicated by average article score of 83%. Aspect of study title formulation had the highest score (95%), while aspect of literature citation had the lowest score (68%). Based on indicators problem formulation, data collection, data analysis, and conclusion formulation, scientific writing on local wisdom in East Java was able to train scientific literation skills to Biology students.