Porous Magnesium-based alloys are biodegradable and promising for use in biomedical applications, especially orthopedics. In this work porous Mg-Zn alloys are successfully synthesized with Mg, Zn, and ammonium hydrogen carbonate (NH₄HCO₃) powder as space holder materials. This research report the preparation of porous magnesium alloys by a powder metallurgy process using ammonium hydrogen carbonate as a space holder particles. The porosity of Mg-Zn alloys depended on the amount of ammonium hydrogen carbonate and was found to have negative effect on corrosion behavior. On the other hand, the degradation resistance can be enhanced by addition of Zn. However, the result of degradation was comparable with that of natural bone. Furthermore, according to the results, the porous Mg–Zn alloys could be considered one of the most promising materials for biomedical application.